The manual transfer of liquid samples is part of daily activities throughout the analytical laboratory. The accurate and precise transfer of liquid samples can be critical to the analytical results. Liquid samples with high viscosities pose several challenges to achieving accurate and precise delivery of desired volumes.
The in vitro metabolic stability of potential drug candidates is routinely examined at an early stage of drug discovery. Metabolic stability is a simple, well-established screening technique used to predict the in vivo hepatic clearance of a drug based on due to metabolism.
Direct thermal extraction (DTE) is a thermal desorption technique in which a small amount of sample, typically 10-50 mg, is placed in an empty fritted thermal desorption tube or into a small vial (μ-vial) within an empty thermal desorption tube.
Antibiotics are a class of antimicrobial veterinary drugs widely used to control disease in food producing animals including egg laying chickens. However, antibiotics can migrate into and accumulate in the egg of the chicken being treated.
This study describes the use of the GERSTEL MultiPurpose Sampler (MPS) fitted with a Thermal Desorption Unit (TDU) and a Cooled Injection System (CIS 4) PTV-type Inlet for the automated direct thermal extraction analysis of packaging for three different brands of crème-filled chocolate...
Food products are routinely monitored for quality, authenticity, and safety. Analysis of food products may also be necessary due to off flavor or odor complaints. The aroma and flavor profiles of each product are unique and made up from a variety of semi-volatile and volatile compounds including aldehydes, ketones, acids,...
A new fully automated thermal desorption (TD)-GC/MS method was developed for determination of formaldehyde and other airborne carbonyls as well as VOCs for material emission testing. The method includes an automated in-situ derivatization agent loading step prior to every sampling step,...
Alcoholic and non-alcoholic beverages are enjoyed by millions of people around the globe. The aroma and flavor profiles of each product are unique and made up from a variety of semi-volatile and volatile compounds including aldehydes, ketones, acids, alcohols, terpenes, esters along with various trace level compounds.
Standard (SBSE) and Solvent-Assisted (SA-SBSE) Stir Bar Sorptive Extraction were both applied for profiling of flavor compounds in a matrix-heavy beverage sample. Unlike standard SBSE, SA-SBSE uses a solvent swollen polydimethylsiloxane (PDMS) stir bar for extraction and enhanced recovery of polar compounds.
A new fully automated thermal desorption (TD)-GC/MS method was developed for determination of formaldehyde and other airborne carbonyls as well as VOCs for material emission testing. The method includes an automated in-situ derivatization agent loading step prior to every sampling step,...