Sample Prep Solution system used for the automated determination of opioids, cocaine and their metabolites in blood serum. The system consists of a GERSTEL MultiPurpose Sampler (MPS) Dual Head version with SPE option and Evaporation Station (mVAP) used for sample preparation and introduction to the GC/MS system, which can be delivered as part of a complete package solution.

Sample Prep Solution

Opioids, cocaine and metabolites

The Opioid Sample Prep Solution enables the determination of cocaine, opioids and their metabolites in blood serum. This Sample Prep Solution was developed in cooperation with Prof. Thomas Daldrup and Dr. Oliver Temme from the Institute of Forensic Medicine at the Heinrich Heine University in Düsseldorf, Germany. A key element in this solution, which can be delivered complete with GC/MS, is the MultiPurpose Sampler (MPS). Following manual protein precipitation and addition of the internal standard, the complete sample preparation is performed automatically (dilution, solid phase extraction, evaporation and derivatization) including introduction to the GC/MS and determination of the analytes.

Calibration ranges:  
Cocaine 5 - 300 ng / mL
Benzoylecgonine 50 - 1500 ng / mL
Methadone 25 - 1500 ng / mL
Morphine 5 - 300 ng / mL
Codeine 2,5 - 150 ng / mL
6-Monoacetylmorphine 2,5 - 150  ng / mL
Dihydrocodeine 5 -300 ng / mL
7-Aminoflunitrazepam 2,5 - 150  ng / mL

Benefits of the GERSTEL Sample Prep Solution for opioids, cocaine and metabolites:

Quantitative determination of opioids, cocaine and metabolites in blood serum

  • Reliable results based on a proven method
  • Reliable quantitation over a wide concentration range

Complete system incl. all methods and detailed description

  • Fast set-up of the system for productive use, no further method development needed

Completely automated sample preparation following protein precipitation and addition of internal standard

  • Improved laboratory safety since less manual handling steps with blood samples are required
  • Reliable and lasting high quality analysis results

Parallel Processing of sample preparation steps during GC/MS analysis

  • Optimized productivity and system utilization
    • During the ongoing analysis, the next sample is prepared
    • As soon as the GC/MS is ready, the next sample is ready to be injected

Upgrade to THC solution available

  • Simple adaptation to future and changing needs
  • Automated determination of THC, THC-OH and THC-COOH 
  • Determination of a range of drugs and metabolites with a single automated analysis system