AppNote

Determination of N-Nitrosamines in Foods


Using Solventless Extraction Techniques

N-nitrosamines, a class of compounds commonly found in foods and beverages, have long been a health concern due to their carcinogenic risks. These compounds are typically formed during food preparation and processing through the reaction of amines with nitrosating compounds. The conventional method of extracting N-nitrosamines utilizes a liquid-liquid extraction with harmful solvents like methylene chloride, a practice that is about to face a significant challenge with the impending EPA ban. This study demonstrates a safer and more efficient solventless extraction approach. Dynamic headspace (DHS) was used to extract N-nitrosamines from a diverse range of sample types.

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