12. November 2012

New AppNote: Analysis of Doping Substances in Equine Urine by DPX-GC/QQQ

A new fully automated dispersive SPE(DPX)-LVI-GC/QqQ method provides fast and reliable results combined with low limits of quantification


This application note describes a fully automated analysis method for selected equine doping compounds in equine urine.
A GERSTEL MultiPurpose Sampler (MPS) with Disposable Pipette Extraction (DPX) option is employed for extraction and cleanup. After gas chromatographic separation the analytes are detected by a triple-quadrupole mass spectrometer (QqQ-MS).
The method is rugged, provides an adequate cleanup of the complex sample matrix and shows good limits of detection, from below 0.1 to just under 10 ng/mL for the various analytes that are determined.


Fully Automated Analysis of Doping Substances in Equine Urine by Disposable Pipette Extraction (DPX) coupled to GC/QqQ-MS